BoltzMaker SSE Comparison | Marc C. Deller

Family coverage

Family	Status	Detail
GLP1R_GNAS+GNB1+GNG2	OK	90 motif row(s) across 9 target(s), annotator=gpcr
GIPR_GNAS+GNB1+GNG2	OK	90 motif row(s) across 9 target(s), annotator=gpcr
GLPAP_GNAS+GNB1+GNG2	No apo structure configured	No 'Apo structure:' configured for this family
GIPAP_GNAS+GNB1+GNG2	No apo structure configured	No 'Apo structure:' configured for this family

Overall shift statistics

6 target(s), 180 motif(s) compared
Mean Ca RMSD: 2.66 A (median 1.58 A) — largest shift: 14.97 A at GLP1R_GNAS+GNB1+GNG2_LSN2 / H8
Mean centroid shift: 1.67 A
Flagged phi/psi outlier residues: 510
Kinase state changes detected: 0 DFG, 0 alphaC

SSE motif shifts (apo vs holo)

Identity						Shift			Helix geometry				Boundary		Backbone
Family	Target	Ligand	Motif	Kind	Source	N res	RMSD (A)	Centroid delta (A)	Axis rot (deg)	Kink apo (deg)	Kink holo (deg)	Kink delta (deg)	Start delta	End delta	Flagged phi/psi
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	H8	helix	gpcr	17	1.20	0.64	6.17	13.34	11.05	-2.29	1.00	2.00	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	H8	helix	gpcr	17	1.12	0.87	4.03	13.34	9.39	-3.96	1.00	2.00	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	H8	helix	gpcr	17	1.18	0.91	4.21	13.34	9.13	-4.21	1.00	7.00	0
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	H8	helix	gpcr	20	2.04	1.69	5.93	5.05	11.74	6.69	142.00	150.00	3
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	H8	helix	gpcr	20	2.06	1.67	6.18	5.05	12.27	7.22	142.00	149.00	3
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	H8	helix	gpcr	20	1.73	1.50	2.95	5.05	8.78	3.74	142.00	149.00	3
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	TM1	helix	gpcr	32	1.08	0.76	1.24	3.49	10.54	7.05	N/A	N/A	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	TM1	helix	gpcr	32	1.75	1.21	4.77	3.49	7.96	4.47	N/A	N/A	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	TM1	helix	gpcr	32	1.34	1.01	2.98	3.49	6.12	2.63	N/A	N/A	1
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	TM1	helix	gpcr	35	3.15	1.99	7.85	8.70	16.12	7.42	N/A	N/A	2
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	TM1	helix	gpcr	35	3.69	2.13	9.85	8.70	15.54	6.84	N/A	N/A	2
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	TM1	helix	gpcr	35	4.60	2.60	11.82	8.70	23.20	14.50	N/A	N/A	2
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	TM2	helix	gpcr	28	2.24	0.68	3.58	17.56	6.33	-11.23	N/A	N/A	4
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	TM2	helix	gpcr	28	1.30	0.56	3.02	17.56	15.36	-2.20	N/A	N/A	2
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	TM2	helix	gpcr	28	1.80	0.80	5.31	17.56	12.38	-5.19	N/A	N/A	2
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	TM2	helix	gpcr	28	0.93	0.59	2.07	4.18	12.85	8.68	N/A	N/A	1
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	TM2	helix	gpcr	28	0.88	0.64	1.23	4.18	10.38	6.20	N/A	N/A	0
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	TM2	helix	gpcr	28	0.99	0.79	0.37	4.18	12.14	7.96	N/A	N/A	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	TM3	helix	gpcr	32	1.19	0.70	2.42	15.22	17.44	2.22	N/A	N/A	2
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	TM3	helix	gpcr	32	1.30	0.91	1.65	15.22	17.50	2.28	N/A	N/A	2
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	TM3	helix	gpcr	32	1.30	0.91	1.85	15.22	16.20	0.98	N/A	N/A	3
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	TM3	helix	gpcr	37	1.08	0.49	2.57	16.75	17.04	0.29	N/A	N/A	1
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	TM3	helix	gpcr	37	0.93	0.72	0.58	16.75	14.80	-1.95	N/A	N/A	0
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	TM3	helix	gpcr	37	1.11	0.85	1.80	16.75	14.58	-2.17	N/A	N/A	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	TM4	helix	gpcr	29	0.76	0.23	2.21	10.55	7.01	-3.54	-11.00	-2.00	2
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	TM4	helix	gpcr	29	0.91	0.35	2.33	10.55	8.39	-2.16	-12.00	-2.00	2
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	TM4	helix	gpcr	29	1.14	0.55	3.08	10.55	8.57	-1.98	-12.00	-2.00	4
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	TM4	helix	gpcr	27	1.14	0.95	0.76	4.63	7.06	2.43	125.00	119.00	3
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	TM4	helix	gpcr	27	1.38	1.20	1.25	4.63	3.79	-0.83	124.00	120.00	3
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	TM4	helix	gpcr	27	1.71	1.51	2.45	4.63	3.33	-1.29	124.00	120.00	3
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	TM5	helix	gpcr	35	2.17	0.72	2.24	7.73	20.05	12.32	1.00	0.00	7
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	TM5	helix	gpcr	35	2.58	1.33	3.90	7.73	18.63	10.90	1.00	0.00	7
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	TM5	helix	gpcr	35	2.61	1.26	4.63	7.73	18.98	11.26	1.00	0.00	7
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	TM5	helix	gpcr	35	1.24	1.02	1.20	18.00	16.71	-1.30	126.00	134.00	1
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	TM5	helix	gpcr	35	1.20	0.85	2.15	18.00	14.72	-3.29	126.00	134.00	0
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	TM5	helix	gpcr	35	1.32	0.88	2.78	18.00	14.58	-3.42	126.00	133.00	1
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	TM6	helix	gpcr	28	9.36	5.68	24.93	19.85	74.11	54.26	-2.00	-7.00	6
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	TM6	helix	gpcr	28	8.86	5.10	24.15	19.85	67.42	47.57	-2.00	-7.00	6
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	TM6	helix	gpcr	28	9.17	5.51	22.90	19.85	75.44	55.59	-2.00	-7.00	8
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	TM6	helix	gpcr	29	7.53	4.46	16.64	30.74	67.89	37.15	121.00	103.00	8
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	TM6	helix	gpcr	29	7.26	4.54	13.74	30.74	69.12	38.37	121.00	103.00	9
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	TM6	helix	gpcr	29	7.52	4.99	13.80	30.74	64.94	34.19	121.00	103.00	9
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	TM7	helix	gpcr	26	6.37	3.41	22.20	40.80	34.73	-6.08	-10.00	-13.00	4
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	TM7	helix	gpcr	26	2.92	1.95	6.73	40.80	35.00	-5.80	-9.00	1.00	3
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	TM7	helix	gpcr	26	6.82	3.76	23.99	40.80	27.78	-13.03	-6.00	-13.00	4
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	TM7	helix	gpcr	29	3.42	1.95	12.67	35.94	33.84	-2.10	157.00	147.00	5
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	TM7	helix	gpcr	29	2.81	1.33	10.61	35.94	24.62	-11.32	157.00	147.00	5
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	TM7	helix	gpcr	29	3.82	2.06	13.86	35.94	20.71	-15.23	157.00	147.00	5
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	ECL2	loop	gpcr	3	1.07	0.82	N/A	N/A	N/A	N/A	N/A	N/A	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	ECL2	loop	gpcr	3	1.09	0.94	N/A	N/A	N/A	N/A	N/A	N/A	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	ECL2	loop	gpcr	3	1.30	1.11	N/A	N/A	N/A	N/A	N/A	N/A	1
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	ECL2	loop	gpcr	3	2.76	1.94	N/A	N/A	N/A	N/A	N/A	N/A	3
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	ECL2	loop	gpcr	3	2.39	1.17	N/A	N/A	N/A	N/A	N/A	N/A	3
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	ECL2	loop	gpcr	3	2.47	1.59	N/A	N/A	N/A	N/A	N/A	N/A	3
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	ICL1	loop	gpcr	4	0.45	0.43	N/A	N/A	N/A	N/A	N/A	N/A	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	ICL1	loop	gpcr	4	0.74	0.70	N/A	N/A	N/A	N/A	N/A	N/A	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN1	LSN1	ICL1	loop	gpcr	4	0.81	0.78	N/A	N/A	N/A	N/A	N/A	N/A	0
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	ICL1	loop	gpcr	4	1.06	0.85	N/A	N/A	N/A	N/A	N/A	N/A	4
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	ICL1	loop	gpcr	4	1.40	1.18	N/A	N/A	N/A	N/A	N/A	N/A	4
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN1	LSN1	ICL1	loop	gpcr	4	1.06	0.80	N/A	N/A	N/A	N/A	N/A	N/A	4
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	H8	helix	gpcr	17	14.97	9.40	101.88	13.34	26.53	13.18	1.00	9.00	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	H8	helix	gpcr	17	1.23	1.10	2.38	13.34	11.36	-1.98	1.00	11.00	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	H8	helix	gpcr	17	1.01	0.76	3.74	13.34	11.38	-1.96	1.00	7.00	0
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	H8	helix	gpcr	20	9.45	3.40	6.16	5.05	133.90	128.85	142.00	142.00	7
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	H8	helix	gpcr	20	2.35	1.88	7.51	5.05	9.89	4.84	142.00	150.00	3
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	H8	helix	gpcr	20	1.94	1.63	4.27	5.05	13.19	8.14	142.00	149.00	3
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	TM1	helix	gpcr	32	4.30	3.92	5.90	3.49	11.56	8.07	N/A	N/A	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	TM1	helix	gpcr	32	2.03	1.33	5.73	3.49	11.68	8.18	N/A	N/A	1
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	TM1	helix	gpcr	32	1.68	1.21	4.16	3.49	9.68	6.19	N/A	N/A	0
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	TM1	helix	gpcr	35	3.50	2.55	7.03	8.70	17.54	8.83	N/A	N/A	4
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	TM1	helix	gpcr	35	3.97	2.17	10.76	8.70	17.63	8.93	N/A	N/A	2
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	TM1	helix	gpcr	35	4.76	2.75	12.58	8.70	23.18	14.48	N/A	N/A	2
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	TM2	helix	gpcr	28	2.74	1.68	8.37	17.56	12.04	-5.52	N/A	N/A	2
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	TM2	helix	gpcr	28	1.48	0.72	3.89	17.56	10.95	-6.61	N/A	N/A	2
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	TM2	helix	gpcr	28	1.74	0.78	5.01	17.56	14.23	-3.33	N/A	N/A	2
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	TM2	helix	gpcr	28	0.83	0.71	0.76	4.18	7.66	3.48	N/A	N/A	0
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	TM2	helix	gpcr	28	1.35	0.90	1.85	4.18	16.29	12.11	N/A	N/A	2
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	TM2	helix	gpcr	28	1.58	0.99	3.43	4.18	16.04	11.87	N/A	N/A	2
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	TM3	helix	gpcr	32	1.50	0.46	4.95	15.22	14.88	-0.34	N/A	N/A	3
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	TM3	helix	gpcr	32	1.59	1.11	2.07	15.22	18.89	3.67	N/A	N/A	3
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	TM3	helix	gpcr	32	1.39	1.00	1.90	15.22	15.16	-0.06	N/A	N/A	2
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	TM3	helix	gpcr	37	0.98	0.70	0.76	16.75	14.16	-2.59	N/A	N/A	0
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	TM3	helix	gpcr	37	1.04	0.78	0.72	16.75	14.69	-2.06	N/A	N/A	0
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	TM3	helix	gpcr	37	1.08	0.82	0.86	16.75	13.35	-3.40	N/A	N/A	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	TM4	helix	gpcr	29	1.69	1.06	4.24	10.55	8.25	-2.31	-12.00	-2.00	3
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	TM4	helix	gpcr	29	1.04	0.47	2.23	10.55	6.86	-3.69	-9.00	0.00	2
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	TM4	helix	gpcr	29	1.01	0.45	2.45	10.55	8.41	-2.14	-12.00	-2.00	2
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	TM4	helix	gpcr	27	1.89	1.55	3.86	4.63	4.64	0.01	128.00	120.00	3
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	TM4	helix	gpcr	27	1.34	1.14	1.11	4.63	4.17	-0.45	124.00	119.00	3
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	TM4	helix	gpcr	27	1.70	1.48	2.40	4.63	3.18	-1.44	126.00	120.00	3
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	TM5	helix	gpcr	35	2.45	1.54	2.08	7.73	18.85	11.12	1.00	0.00	6
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	TM5	helix	gpcr	35	2.68	1.45	4.22	7.73	17.86	10.13	-3.00	0.00	6
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	TM5	helix	gpcr	35	2.77	1.38	4.92	7.73	19.58	11.85	1.00	0.00	7
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	TM5	helix	gpcr	35	2.27	1.88	3.33	18.00	20.18	2.17	126.00	132.00	1
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	TM5	helix	gpcr	35	1.08	0.74	1.80	18.00	12.83	-5.18	126.00	133.00	1
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	TM5	helix	gpcr	35	1.24	0.92	1.62	18.00	17.55	-0.46	126.00	133.00	1
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	TM6	helix	gpcr	28	9.04	6.06	19.04	19.85	74.87	55.02	-2.00	-7.00	5
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	TM6	helix	gpcr	28	8.94	5.15	24.44	19.85	68.54	48.68	-2.00	-7.00	6
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	TM6	helix	gpcr	28	8.97	5.25	23.67	19.85	71.88	52.03	-2.00	-7.00	6
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	TM6	helix	gpcr	29	8.39	5.86	18.01	30.74	64.28	33.53	121.00	103.00	8
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	TM6	helix	gpcr	29	7.36	4.67	13.16	30.74	70.23	39.49	121.00	103.00	8
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	TM6	helix	gpcr	29	7.33	4.50	14.62	30.74	66.60	35.85	121.00	103.00	8
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	TM7	helix	gpcr	26	7.14	5.51	10.74	40.80	54.16	13.36	-8.00	-2.00	7
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	TM7	helix	gpcr	26	3.21	2.11	8.01	40.80	35.05	-5.75	-8.00	1.00	3
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	TM7	helix	gpcr	26	7.09	3.94	25.00	40.80	30.47	-10.34	-6.00	-13.00	4
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	TM7	helix	gpcr	29	2.78	2.15	7.29	35.94	34.02	-1.92	157.00	147.00	5
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	TM7	helix	gpcr	29	3.08	1.42	11.84	35.94	24.07	-11.88	157.00	147.00	5
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	TM7	helix	gpcr	29	4.08	2.26	15.03	35.94	23.20	-12.74	157.00	147.00	5
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	ECL2	loop	gpcr	3	2.04	1.84	N/A	N/A	N/A	N/A	N/A	N/A	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	ECL2	loop	gpcr	3	1.56	1.42	N/A	N/A	N/A	N/A	N/A	N/A	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	ECL2	loop	gpcr	3	1.18	0.95	N/A	N/A	N/A	N/A	N/A	N/A	0
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	ECL2	loop	gpcr	3	2.64	1.65	N/A	N/A	N/A	N/A	N/A	N/A	3
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	ECL2	loop	gpcr	3	2.11	0.41	N/A	N/A	N/A	N/A	N/A	N/A	3
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	ECL2	loop	gpcr	3	2.56	1.61	N/A	N/A	N/A	N/A	N/A	N/A	3
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	ICL1	loop	gpcr	4	4.36	4.34	N/A	N/A	N/A	N/A	N/A	N/A	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	ICL1	loop	gpcr	4	0.90	0.84	N/A	N/A	N/A	N/A	N/A	N/A	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_LSN2	LSN2	ICL1	loop	gpcr	4	0.78	0.76	N/A	N/A	N/A	N/A	N/A	N/A	0
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	ICL1	loop	gpcr	4	1.16	0.98	N/A	N/A	N/A	N/A	N/A	N/A	4
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	ICL1	loop	gpcr	4	1.15	0.95	N/A	N/A	N/A	N/A	N/A	N/A	4
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_LSN2	LSN2	ICL1	loop	gpcr	4	1.27	0.96	N/A	N/A	N/A	N/A	N/A	N/A	4
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	H8	helix	gpcr	17	1.11	0.59	5.28	13.34	14.55	1.21	1.00	1.00	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	H8	helix	gpcr	17	0.85	0.52	3.06	13.34	13.10	-0.24	1.00	6.00	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	H8	helix	gpcr	17	0.96	0.85	0.85	13.34	13.48	0.14	1.00	6.00	1
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	H8	helix	gpcr	20	2.54	2.03	9.03	5.05	9.39	4.35	142.00	149.00	3
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	H8	helix	gpcr	20	2.29	1.91	6.25	5.05	12.47	7.43	142.00	149.00	3
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	H8	helix	gpcr	20	1.96	1.71	4.71	5.05	12.05	7.00	142.00	149.00	3
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	TM1	helix	gpcr	32	0.92	0.67	1.73	3.49	9.59	6.10	N/A	N/A	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	TM1	helix	gpcr	32	0.87	0.68	1.52	3.49	2.02	-1.47	N/A	N/A	1
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	TM1	helix	gpcr	32	1.30	0.92	2.84	3.49	5.71	2.21	N/A	N/A	1
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	TM1	helix	gpcr	35	2.39	1.62	5.73	8.70	7.35	-1.35	N/A	N/A	2
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	TM1	helix	gpcr	35	3.58	1.92	9.72	8.70	15.96	7.26	N/A	N/A	2
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	TM1	helix	gpcr	35	3.79	2.21	9.80	8.70	17.34	8.64	N/A	N/A	3
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	TM2	helix	gpcr	28	2.21	0.53	4.26	17.56	6.97	-10.60	N/A	N/A	2
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	TM2	helix	gpcr	28	1.47	0.73	3.97	17.56	13.71	-3.85	N/A	N/A	2
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	TM2	helix	gpcr	28	1.54	0.72	4.40	17.56	16.51	-1.05	N/A	N/A	2
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	TM2	helix	gpcr	28	0.99	0.80	0.73	4.18	12.91	8.74	N/A	N/A	0
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	TM2	helix	gpcr	28	0.96	0.68	1.26	4.18	12.29	8.11	N/A	N/A	0
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	TM2	helix	gpcr	28	0.78	0.64	0.45	4.18	8.85	4.68	N/A	N/A	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	TM3	helix	gpcr	32	1.28	0.71	2.60	15.22	14.05	-1.17	N/A	N/A	2
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	TM3	helix	gpcr	32	1.39	1.02	1.25	15.22	20.73	5.50	N/A	N/A	2
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	TM3	helix	gpcr	32	1.48	1.11	1.11	15.22	18.17	2.95	N/A	N/A	3
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	TM3	helix	gpcr	37	0.95	0.65	2.11	16.75	16.25	-0.50	N/A	N/A	1
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	TM3	helix	gpcr	37	0.93	0.73	0.40	16.75	15.61	-1.14	N/A	N/A	1
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	TM3	helix	gpcr	37	1.00	0.77	1.07	16.75	12.44	-4.31	N/A	N/A	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	TM4	helix	gpcr	29	0.78	0.21	1.75	10.55	7.78	-2.77	-9.00	-2.00	1
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	TM4	helix	gpcr	29	1.05	0.38	2.66	10.55	9.53	-1.02	-12.00	-2.00	2
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	TM4	helix	gpcr	29	1.27	0.33	4.21	10.55	8.41	-2.14	-9.00	-2.00	2
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	TM4	helix	gpcr	27	1.18	0.91	2.20	4.63	5.96	1.33	127.00	120.00	3
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	TM4	helix	gpcr	27	1.25	1.06	0.69	4.63	6.82	2.19	128.00	120.00	3
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	TM4	helix	gpcr	27	1.31	1.14	0.90	4.63	4.83	0.20	124.00	120.00	3
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	TM5	helix	gpcr	35	2.23	0.80	2.78	7.73	17.31	9.58	1.00	0.00	8
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	TM5	helix	gpcr	35	2.48	1.18	2.87	7.73	21.56	13.83	1.00	0.00	11
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	TM5	helix	gpcr	35	2.42	1.20	3.31	7.73	18.41	10.68	1.00	0.00	12
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	TM5	helix	gpcr	35	1.03	0.56	1.24	18.00	15.11	-2.90	126.00	134.00	2
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	TM5	helix	gpcr	35	1.11	0.74	1.69	18.00	12.53	-5.48	126.00	134.00	0
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	TM5	helix	gpcr	35	1.09	0.87	0.85	18.00	14.99	-3.02	126.00	133.00	1
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	TM6	helix	gpcr	28	8.81	4.96	24.38	19.85	64.65	44.80	-2.00	-7.00	6
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	TM6	helix	gpcr	28	9.08	5.41	23.02	19.85	77.94	58.09	-2.00	-7.00	9
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	TM6	helix	gpcr	28	8.81	5.14	23.30	19.85	69.57	49.72	-2.00	-7.00	9
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	TM6	helix	gpcr	29	7.24	4.71	11.52	30.74	71.43	40.69	121.00	103.00	8
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	TM6	helix	gpcr	29	7.18	4.47	13.29	30.74	67.77	37.03	121.00	103.00	7
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	TM6	helix	gpcr	29	7.20	4.24	15.46	30.74	68.39	37.65	121.00	103.00	7
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	TM7	helix	gpcr	26	2.52	1.37	4.44	40.80	39.53	-1.27	-8.00	1.00	3
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	TM7	helix	gpcr	26	5.36	3.17	18.84	40.80	35.46	-5.34	-9.00	1.00	2
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	TM7	helix	gpcr	26	5.41	2.81	19.34	40.80	17.86	-22.94	-9.00	1.00	3
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	TM7	helix	gpcr	29	2.00	0.67	7.41	35.94	25.47	-10.48	157.00	147.00	5
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	TM7	helix	gpcr	29	3.00	1.40	11.43	35.94	22.47	-13.47	157.00	147.00	5
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	TM7	helix	gpcr	29	3.15	1.71	11.66	35.94	27.10	-8.84	157.00	147.00	5
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	ECL2	loop	gpcr	3	1.29	1.00	N/A	N/A	N/A	N/A	N/A	N/A	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	ECL2	loop	gpcr	3	1.31	1.10	N/A	N/A	N/A	N/A	N/A	N/A	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	ECL2	loop	gpcr	3	1.54	1.36	N/A	N/A	N/A	N/A	N/A	N/A	2
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	ECL2	loop	gpcr	3	2.28	1.54	N/A	N/A	N/A	N/A	N/A	N/A	3
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	ECL2	loop	gpcr	3	2.09	0.89	N/A	N/A	N/A	N/A	N/A	N/A	3
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	ECL2	loop	gpcr	3	2.25	1.13	N/A	N/A	N/A	N/A	N/A	N/A	3
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	ICL1	loop	gpcr	4	0.47	0.45	N/A	N/A	N/A	N/A	N/A	N/A	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	ICL1	loop	gpcr	4	0.56	0.54	N/A	N/A	N/A	N/A	N/A	N/A	0
GLP1R_GNAS+GNB1+GNG2	GLP1R_GNAS+GNB1+GNG2_ORFO	ORFO	ICL1	loop	gpcr	4	0.70	0.69	N/A	N/A	N/A	N/A	N/A	N/A	0
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	ICL1	loop	gpcr	4	1.14	0.96	N/A	N/A	N/A	N/A	N/A	N/A	4
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	ICL1	loop	gpcr	4	1.02	0.73	N/A	N/A	N/A	N/A	N/A	N/A	4
GIPR_GNAS+GNB1+GNG2	GIPR_GNAS+GNB1+GNG2_ORFO	ORFO	ICL1	loop	gpcr	4	1.18	0.88	N/A	N/A	N/A	N/A	N/A	N/A	4

Download CSV

BoltzMaker Report

Family coverage

Overall shift statistics

SSE motif shifts (apo vs holo)

Per-motif Ca RMSD

Motif x target RMSD