BoltzMaker SSE Comparison | Marc C. Deller

Family coverage

Family	Status	Detail
HTR2A_GNAI1+GNB1+GNG2	OK	13 motif row(s) across 1 target(s), annotator=gpcr
HTRAP_GNAI1+GNB1+GNG2	No apo structure configured	No 'Apo structure:' configured for this family

1 target(s), 13 motif(s) compared
Mean Ca RMSD: 1.03 A (median 0.92 A) — largest shift: 2.50 A at HTR2A_GNAI1+GNB1+GNG2_8NU / ICL2
Mean centroid shift: 0.77 A
Flagged phi/psi outlier residues: 19
Kinase state changes detected: 0 DFG, 0 alphaC

Identity						Shift			Helix geometry				Boundary		Backbone
Family	Target	Ligand	Motif	Kind	Source	N res	RMSD (A)	Centroid delta (A)	Axis rot (deg)	Kink apo (deg)	Kink holo (deg)	Kink delta (deg)	Start delta	End delta	Flagged phi/psi
HTR2A_GNAI1+GNB1+GNG2	HTR2A_GNAI1+GNB1+GNG2_8NU	8NU	H8	helix	gpcr	10	0.85	0.76	3.82	18.98	23.78	4.80	142.00	134.00	0
HTR2A_GNAI1+GNB1+GNG2	HTR2A_GNAI1+GNB1+GNG2_8NU	8NU	TM1	helix	gpcr	25	1.09	0.97	1.36	10.92	6.30	-4.62	N/A	N/A	2
HTR2A_GNAI1+GNB1+GNG2	HTR2A_GNAI1+GNB1+GNG2_8NU	8NU	TM2	helix	gpcr	31	0.84	0.56	1.49	19.22	21.79	2.57	N/A	N/A	1
HTR2A_GNAI1+GNB1+GNG2	HTR2A_GNAI1+GNB1+GNG2_8NU	8NU	TM3	helix	gpcr	36	0.61	0.17	0.60	7.36	11.03	3.67	66.00	77.00	0
HTR2A_GNAI1+GNB1+GNG2	HTR2A_GNAI1+GNB1+GNG2_8NU	8NU	TM4	helix	gpcr	30	0.86	0.44	0.82	24.62	27.32	2.70	82.00	80.00	0
HTR2A_GNAI1+GNB1+GNG2	HTR2A_GNAI1+GNB1+GNG2_8NU	8NU	TM5	helix	gpcr	31	1.00	0.87	1.10	9.07	9.40	0.33	85.00	86.00	3
HTR2A_GNAI1+GNB1+GNG2	HTR2A_GNAI1+GNB1+GNG2_8NU	8NU	TM6	helix	gpcr	35	0.74	0.68	0.06	29.00	29.19	0.18	124.00	140.00	1
HTR2A_GNAI1+GNB1+GNG2	HTR2A_GNAI1+GNB1+GNG2_8NU	8NU	TM7	helix	gpcr	30	0.69	0.21	1.35	29.08	26.93	-2.15	123.00	138.00	4
HTR2A_GNAI1+GNB1+GNG2	HTR2A_GNAI1+GNB1+GNG2_8NU	8NU	ECL1	loop	gpcr	4	1.00	0.94	N/A	N/A	N/A	N/A	N/A	N/A	2
HTR2A_GNAI1+GNB1+GNG2	HTR2A_GNAI1+GNB1+GNG2_8NU	8NU	ECL2	loop	gpcr	3	0.96	0.85	N/A	N/A	N/A	N/A	79.00	48.00	0
HTR2A_GNAI1+GNB1+GNG2	HTR2A_GNAI1+GNB1+GNG2_8NU	8NU	ICL1	loop	gpcr	4	0.92	0.89	N/A	N/A	N/A	N/A	N/A	N/A	2
HTR2A_GNAI1+GNB1+GNG2	HTR2A_GNAI1+GNB1+GNG2_8NU	8NU	ICL2	loop	gpcr	9	2.50	1.38	N/A	N/A	N/A	N/A	82.00	80.00	4
HTR2A_GNAI1+GNB1+GNG2	HTR2A_GNAI1+GNB1+GNG2_8NU	8NU	ICL3	loop	gpcr	1	1.33	1.33	N/A	N/A	N/A	N/A	N/A	N/A	0