BoltzMaker SSE Comparison | Marc C. Deller

Family coverage

Family	Status	Detail
5HT2A_GNAQ+GNB1+GNG2	OK	28 motif row(s) across 2 target(s), annotator=gpcr
5HT2A	OK	28 motif row(s) across 2 target(s), annotator=gpcr
5HT2A	No apo structure configured	No 'Apo structure:' configured for this family
5HT2B_GNAQ+GNB1+GNG2	OK	28 motif row(s) across 2 target(s), annotator=gpcr
5HT2B	OK	28 motif row(s) across 2 target(s), annotator=gpcr
5HT2B	No apo structure configured	No 'Apo structure:' configured for this family
5HT2C_GNAQ+GNB1+GNG2	OK	26 motif row(s) across 2 target(s), annotator=gpcr
5HT2C	OK	26 motif row(s) across 2 target(s), annotator=gpcr
5HT2C	No apo structure configured	No 'Apo structure:' configured for this family

Overall shift statistics

12 target(s), 164 motif(s) compared
Mean Ca RMSD: 4.96 A (median 1.77 A) — largest shift: 30.34 A at 5HT2C_GNAQ+GNB1+GNG2_LORC / ECL2
Mean centroid shift: 2.86 A
Flagged phi/psi outlier residues: 164
Kinase state changes detected: 0 DFG, 0 alphaC

SSE motif shifts (apo vs holo)

Identity						Shift			Helix geometry				Backbone
Family	Target	Ligand	Motif	Kind	Source	N res	RMSD (A)	Centroid delta (A)	Axis rot (deg)	Kink apo (deg)	Kink holo (deg)	Kink delta (deg)	Flagged phi/psi
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_BALO	BALO	H8	helix	gpcr	12	1.35	1.30	2.81	35.47	35.18	-0.29	0
5HT2B	5HT2B_BALO	BALO	H8	helix	gpcr	12	0.35	0.27	1.42	35.47	33.74	-1.73	0
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_BALO	BALO	TM1	helix	gpcr	29	2.38	1.82	6.62	15.87	10.25	-5.62	0
5HT2B	5HT2B_BALO	BALO	TM1	helix	gpcr	29	0.83	0.68	1.64	15.87	19.49	3.62	0
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_BALO	BALO	TM2	helix	gpcr	30	2.15	1.37	6.50	9.04	16.89	7.84	0
5HT2B	5HT2B_BALO	BALO	TM2	helix	gpcr	30	1.37	1.04	3.19	9.04	15.18	6.14	0
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_BALO	BALO	TM3	helix	gpcr	36	1.72	1.35	3.29	20.29	14.69	-5.59	0
5HT2B	5HT2B_BALO	BALO	TM3	helix	gpcr	36	1.08	0.56	3.21	20.29	20.08	-0.21	0
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_BALO	BALO	TM4	helix	gpcr	27	1.84	1.68	3.24	23.57	21.58	-1.98	0
5HT2B	5HT2B_BALO	BALO	TM4	helix	gpcr	27	1.18	1.02	1.97	23.57	16.80	-6.77	1
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_BALO	BALO	TM5	helix	gpcr	41	2.73	2.19	2.78	13.03	2.27	-10.76	2
5HT2B	5HT2B_BALO	BALO	TM5	helix	gpcr	41	1.36	0.38	3.09	13.03	8.65	-4.39	2
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_BALO	BALO	TM6	helix	gpcr	38	2.68	2.11	3.37	32.50	28.33	-4.18	0
5HT2B	5HT2B_BALO	BALO	TM6	helix	gpcr	38	1.18	0.39	3.73	32.50	33.48	0.98	0
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_BALO	BALO	TM7	helix	gpcr	30	1.73	1.40	4.12	27.07	27.15	0.07	0
5HT2B	5HT2B_BALO	BALO	TM7	helix	gpcr	30	1.07	0.99	1.38	27.07	26.99	-0.08	0
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_BALO	BALO	ECL1	loop	gpcr	4	2.36	2.34	N/A	N/A	N/A	N/A	1
5HT2B	5HT2B_BALO	BALO	ECL1	loop	gpcr	4	2.28	2.23	N/A	N/A	N/A	N/A	0
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_BALO	BALO	ECL2	loop	gpcr	12	20.40	8.37	N/A	N/A	N/A	N/A	4
5HT2B	5HT2B_BALO	BALO	ECL2	loop	gpcr	12	11.20	5.44	N/A	N/A	N/A	N/A	1
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_BALO	BALO	ECL3	loop	gpcr	1	1.34	1.34	N/A	N/A	N/A	N/A	0
5HT2B	5HT2B_BALO	BALO	ECL3	loop	gpcr	1	0.49	0.49	N/A	N/A	N/A	N/A	0
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_BALO	BALO	ICL1	loop	gpcr	4	1.68	1.68	N/A	N/A	N/A	N/A	0
5HT2B	5HT2B_BALO	BALO	ICL1	loop	gpcr	4	0.72	0.71	N/A	N/A	N/A	N/A	0
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_BALO	BALO	ICL2	loop	gpcr	13	22.18	12.67	N/A	N/A	N/A	N/A	5
5HT2B	5HT2B_BALO	BALO	ICL2	loop	gpcr	13	8.23	2.46	N/A	N/A	N/A	N/A	7
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_BALO	BALO	ICL3	loop	gpcr	6	24.68	16.27	N/A	N/A	N/A	N/A	1
5HT2B	5HT2B_BALO	BALO	ICL3	loop	gpcr	6	18.16	12.17	N/A	N/A	N/A	N/A	0
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_LORC	LORC	H8	helix	gpcr	14	3.42	3.30	7.87	2.59	2.47	-0.12	0
5HT2C	5HT2C_LORC	LORC	H8	helix	gpcr	14	1.03	0.88	4.68	2.59	7.33	4.74	0
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_LORC	LORC	TM1	helix	gpcr	28	3.12	1.36	5.44	20.75	9.96	-10.79	4
5HT2C	5HT2C_LORC	LORC	TM1	helix	gpcr	28	1.96	0.69	4.72	20.75	6.81	-13.95	1
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_LORC	LORC	TM2	helix	gpcr	31	1.41	0.87	4.53	19.91	20.63	0.72	0
5HT2C	5HT2C_LORC	LORC	TM2	helix	gpcr	31	0.62	0.57	0.74	19.91	19.80	-0.10	0
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_LORC	LORC	TM3	helix	gpcr	36	2.06	1.46	5.09	16.10	10.47	-5.63	0
5HT2C	5HT2C_LORC	LORC	TM3	helix	gpcr	36	0.66	0.46	1.52	16.10	15.19	-0.91	0
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_LORC	LORC	TM4	helix	gpcr	30	1.98	1.50	5.00	26.43	20.31	-6.12	0
5HT2C	5HT2C_LORC	LORC	TM4	helix	gpcr	30	0.33	0.14	0.91	26.43	27.61	1.18	0
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_LORC	LORC	TM5	helix	gpcr	39	3.08	2.62	4.04	5.64	7.85	2.22	1
5HT2C	5HT2C_LORC	LORC	TM5	helix	gpcr	39	1.60	1.13	3.19	5.64	6.08	0.44	1
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_LORC	LORC	TM6	helix	gpcr	38	2.86	2.16	4.99	31.72	28.37	-3.35	0
5HT2C	5HT2C_LORC	LORC	TM6	helix	gpcr	38	1.39	1.03	2.58	31.72	36.55	4.83	0
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_LORC	LORC	TM7	helix	gpcr	30	1.79	1.28	5.01	27.10	29.84	2.74	0
5HT2C	5HT2C_LORC	LORC	TM7	helix	gpcr	30	0.73	0.68	0.30	27.10	25.46	-1.64	0
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_LORC	LORC	ECL1	loop	gpcr	4	1.96	1.94	N/A	N/A	N/A	N/A	0
5HT2C	5HT2C_LORC	LORC	ECL1	loop	gpcr	4	1.00	0.99	N/A	N/A	N/A	N/A	0
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_LORC	LORC	ECL2	loop	gpcr	10	30.34	19.95	N/A	N/A	N/A	N/A	1
5HT2C	5HT2C_LORC	LORC	ECL2	loop	gpcr	10	17.29	10.65	N/A	N/A	N/A	N/A	1
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_LORC	LORC	ICL1	loop	gpcr	4	2.51	2.49	N/A	N/A	N/A	N/A	0
5HT2C	5HT2C_LORC	LORC	ICL1	loop	gpcr	4	0.48	0.46	N/A	N/A	N/A	N/A	0
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_LORC	LORC	ICL2	loop	gpcr	20	19.38	11.37	N/A	N/A	N/A	N/A	5
5HT2C	5HT2C_LORC	LORC	ICL2	loop	gpcr	20	9.15	3.32	N/A	N/A	N/A	N/A	7
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_LORC	LORC	ICL3	loop	gpcr	2	22.48	13.94	N/A	N/A	N/A	N/A	0
5HT2C	5HT2C_LORC	LORC	ICL3	loop	gpcr	2	29.85	20.40	N/A	N/A	N/A	N/A	0
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_LSD1	LSD1	H8	helix	gpcr	12	1.98	1.97	1.00	35.47	34.61	-0.86	0
5HT2B	5HT2B_LSD1	LSD1	H8	helix	gpcr	12	0.99	0.96	1.60	35.47	33.09	-2.38	0
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_LSD1	LSD1	TM1	helix	gpcr	29	1.97	1.30	6.19	15.87	7.34	-8.52	0
5HT2B	5HT2B_LSD1	LSD1	TM1	helix	gpcr	29	0.93	0.64	2.92	15.87	15.55	-0.31	0
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_LSD1	LSD1	TM2	helix	gpcr	30	1.87	0.35	7.16	9.04	16.76	7.72	0
5HT2B	5HT2B_LSD1	LSD1	TM2	helix	gpcr	30	1.02	0.59	3.17	9.04	12.79	3.75	0
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_LSD1	LSD1	TM3	helix	gpcr	36	1.88	1.38	4.07	20.29	13.02	-7.27	0
5HT2B	5HT2B_LSD1	LSD1	TM3	helix	gpcr	36	0.94	0.56	2.70	20.29	19.17	-1.12	0
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_LSD1	LSD1	TM4	helix	gpcr	27	2.26	1.86	5.96	23.57	19.17	-4.39	1
5HT2B	5HT2B_LSD1	LSD1	TM4	helix	gpcr	27	1.12	0.96	2.00	23.57	18.45	-5.12	1
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_LSD1	LSD1	TM5	helix	gpcr	41	4.54	3.32	6.41	13.03	16.48	3.44	2
5HT2B	5HT2B_LSD1	LSD1	TM5	helix	gpcr	41	1.09	0.11	2.83	13.03	11.32	-1.72	0
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_LSD1	LSD1	TM6	helix	gpcr	38	4.61	2.38	7.60	32.50	23.91	-8.60	4
5HT2B	5HT2B_LSD1	LSD1	TM6	helix	gpcr	38	1.36	0.72	3.84	32.50	35.14	2.64	0
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_LSD1	LSD1	TM7	helix	gpcr	30	1.63	0.54	6.44	27.07	29.63	2.56	0
5HT2B	5HT2B_LSD1	LSD1	TM7	helix	gpcr	30	1.04	0.89	2.24	27.07	26.03	-1.04	0
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_LSD1	LSD1	ECL1	loop	gpcr	4	2.33	2.30	N/A	N/A	N/A	N/A	1
5HT2B	5HT2B_LSD1	LSD1	ECL1	loop	gpcr	4	2.12	2.09	N/A	N/A	N/A	N/A	0
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_LSD1	LSD1	ECL2	loop	gpcr	12	21.59	9.69	N/A	N/A	N/A	N/A	3
5HT2B	5HT2B_LSD1	LSD1	ECL2	loop	gpcr	12	11.70	5.07	N/A	N/A	N/A	N/A	2
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_LSD1	LSD1	ECL3	loop	gpcr	1	1.75	1.75	N/A	N/A	N/A	N/A	0
5HT2B	5HT2B_LSD1	LSD1	ECL3	loop	gpcr	1	1.45	1.45	N/A	N/A	N/A	N/A	0
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_LSD1	LSD1	ICL1	loop	gpcr	4	2.35	2.35	N/A	N/A	N/A	N/A	0
5HT2B	5HT2B_LSD1	LSD1	ICL1	loop	gpcr	4	0.74	0.73	N/A	N/A	N/A	N/A	0
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_LSD1	LSD1	ICL2	loop	gpcr	13	25.49	13.10	N/A	N/A	N/A	N/A	5
5HT2B	5HT2B_LSD1	LSD1	ICL2	loop	gpcr	13	8.32	1.41	N/A	N/A	N/A	N/A	9
5HT2B_GNAQ+GNB1+GNG2	5HT2B_GNAQ+GNB1+GNG2_LSD1	LSD1	ICL3	loop	gpcr	6	13.86	5.67	N/A	N/A	N/A	N/A	0
5HT2B	5HT2B_LSD1	LSD1	ICL3	loop	gpcr	6	15.01	7.46	N/A	N/A	N/A	N/A	0
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_PSIL	PSIL	H8	helix	gpcr	14	1.63	0.76	12.92	4.38	1.07	-3.31	0
5HT2A	5HT2A_PSIL	PSIL	H8	helix	gpcr	14	0.83	0.49	5.77	4.38	2.14	-2.24	0
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_PSIL	PSIL	TM1	helix	gpcr	34	2.07	1.38	4.44	39.16	38.53	-0.63	4
5HT2A	5HT2A_PSIL	PSIL	TM1	helix	gpcr	34	0.80	0.48	2.15	39.16	38.28	-0.89	2
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_PSIL	PSIL	TM2	helix	gpcr	31	1.01	0.35	3.55	23.86	19.35	-4.52	1
5HT2A	5HT2A_PSIL	PSIL	TM2	helix	gpcr	31	0.49	0.28	1.61	23.86	22.78	-1.08	0
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_PSIL	PSIL	TM3	helix	gpcr	36	1.46	1.03	2.73	19.57	10.90	-8.68	0
5HT2A	5HT2A_PSIL	PSIL	TM3	helix	gpcr	36	0.58	0.46	0.71	19.57	20.52	0.95	0
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_PSIL	PSIL	TM4	helix	gpcr	30	0.93	0.87	0.90	25.02	23.88	-1.15	0
5HT2A	5HT2A_PSIL	PSIL	TM4	helix	gpcr	30	0.75	0.52	2.01	25.02	28.63	3.61	1
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_PSIL	PSIL	TM5	helix	gpcr	41	3.22	1.73	6.51	6.90	6.44	-0.45	3
5HT2A	5HT2A_PSIL	PSIL	TM5	helix	gpcr	41	1.29	0.90	1.07	6.90	2.85	-4.05	2
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_PSIL	PSIL	TM6	helix	gpcr	38	2.50	1.97	4.34	29.68	26.82	-2.87	0
5HT2A	5HT2A_PSIL	PSIL	TM6	helix	gpcr	38	2.50	0.82	7.21	29.68	35.90	6.22	0
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_PSIL	PSIL	TM7	helix	gpcr	30	2.15	1.63	4.06	28.17	27.23	-0.94	2
5HT2A	5HT2A_PSIL	PSIL	TM7	helix	gpcr	30	1.03	0.76	2.57	28.17	28.00	-0.16	0
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_PSIL	PSIL	ECL1	loop	gpcr	4	0.81	0.78	N/A	N/A	N/A	N/A	0
5HT2A	5HT2A_PSIL	PSIL	ECL1	loop	gpcr	4	0.71	0.71	N/A	N/A	N/A	N/A	0
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_PSIL	PSIL	ECL2	loop	gpcr	16	27.27	8.03	N/A	N/A	N/A	N/A	5
5HT2A	5HT2A_PSIL	PSIL	ECL2	loop	gpcr	16	18.31	8.94	N/A	N/A	N/A	N/A	3
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_PSIL	PSIL	ECL3	loop	gpcr	1	0.66	0.66	N/A	N/A	N/A	N/A	0
5HT2A	5HT2A_PSIL	PSIL	ECL3	loop	gpcr	1	1.00	1.00	N/A	N/A	N/A	N/A	0
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_PSIL	PSIL	H8loop	loop	gpcr	1	1.08	1.08	N/A	N/A	N/A	N/A	0
5HT2A	5HT2A_PSIL	PSIL	H8loop	loop	gpcr	1	0.88	0.88	N/A	N/A	N/A	N/A	0
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_PSIL	PSIL	ICL1	loop	gpcr	4	1.34	1.30	N/A	N/A	N/A	N/A	1
5HT2A	5HT2A_PSIL	PSIL	ICL1	loop	gpcr	4	0.42	0.34	N/A	N/A	N/A	N/A	0
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_PSIL	PSIL	ICL2	loop	gpcr	15	24.72	11.50	N/A	N/A	N/A	N/A	5
5HT2A	5HT2A_PSIL	PSIL	ICL2	loop	gpcr	15	14.63	5.01	N/A	N/A	N/A	N/A	4
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_RISP	RISP	H8	helix	gpcr	14	1.73	0.67	14.40	4.38	3.23	-1.15	0
5HT2A	5HT2A_RISP	RISP	H8	helix	gpcr	14	0.71	0.37	5.21	4.38	0.84	-3.54	0
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_RISP	RISP	TM1	helix	gpcr	34	2.03	1.24	4.13	39.16	41.58	2.41	2
5HT2A	5HT2A_RISP	RISP	TM1	helix	gpcr	34	0.66	0.15	0.71	39.16	39.10	-0.07	3
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_RISP	RISP	TM2	helix	gpcr	31	1.21	0.42	4.17	23.86	17.76	-6.10	1
5HT2A	5HT2A_RISP	RISP	TM2	helix	gpcr	31	0.25	0.07	0.65	23.86	21.73	-2.14	0
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_RISP	RISP	TM3	helix	gpcr	36	1.16	0.83	2.10	19.57	12.72	-6.85	0
5HT2A	5HT2A_RISP	RISP	TM3	helix	gpcr	36	0.46	0.16	1.07	19.57	20.66	1.09	1
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_RISP	RISP	TM4	helix	gpcr	30	0.99	0.90	0.93	25.02	25.79	0.77	0
5HT2A	5HT2A_RISP	RISP	TM4	helix	gpcr	30	0.62	0.15	2.24	25.02	27.89	2.87	1
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_RISP	RISP	TM5	helix	gpcr	41	3.26	1.18	4.77	6.90	9.06	2.17	2
5HT2A	5HT2A_RISP	RISP	TM5	helix	gpcr	41	1.22	0.70	0.49	6.90	5.59	-1.30	2
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_RISP	RISP	TM6	helix	gpcr	38	2.68	2.34	3.56	29.68	30.40	0.72	0
5HT2A	5HT2A_RISP	RISP	TM6	helix	gpcr	38	2.51	0.73	7.70	29.68	32.36	2.68	0
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_RISP	RISP	TM7	helix	gpcr	30	2.59	1.77	6.70	28.17	27.31	-0.86	3
5HT2A	5HT2A_RISP	RISP	TM7	helix	gpcr	30	1.14	0.71	3.56	28.17	29.32	1.15	0
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_RISP	RISP	ECL1	loop	gpcr	4	0.87	0.86	N/A	N/A	N/A	N/A	0
5HT2A	5HT2A_RISP	RISP	ECL1	loop	gpcr	4	0.42	0.38	N/A	N/A	N/A	N/A	0
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_RISP	RISP	ECL2	loop	gpcr	16	28.31	10.45	N/A	N/A	N/A	N/A	5
5HT2A	5HT2A_RISP	RISP	ECL2	loop	gpcr	16	16.66	9.35	N/A	N/A	N/A	N/A	3
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_RISP	RISP	ECL3	loop	gpcr	1	0.51	0.51	N/A	N/A	N/A	N/A	0
5HT2A	5HT2A_RISP	RISP	ECL3	loop	gpcr	1	0.97	0.97	N/A	N/A	N/A	N/A	0
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_RISP	RISP	H8loop	loop	gpcr	1	0.94	0.94	N/A	N/A	N/A	N/A	0
5HT2A	5HT2A_RISP	RISP	H8loop	loop	gpcr	1	0.68	0.68	N/A	N/A	N/A	N/A	0
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_RISP	RISP	ICL1	loop	gpcr	4	1.89	1.87	N/A	N/A	N/A	N/A	0
5HT2A	5HT2A_RISP	RISP	ICL1	loop	gpcr	4	0.29	0.18	N/A	N/A	N/A	N/A	0
5HT2A_GNAQ+GNB1+GNG2	5HT2A_GNAQ+GNB1+GNG2_RISP	RISP	ICL2	loop	gpcr	15	18.71	9.43	N/A	N/A	N/A	N/A	6
5HT2A	5HT2A_RISP	RISP	ICL2	loop	gpcr	15	14.77	2.36	N/A	N/A	N/A	N/A	8
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_SB24	SB24	H8	helix	gpcr	14	3.36	3.23	8.44	2.59	2.23	-0.36	0
5HT2C	5HT2C_SB24	SB24	H8	helix	gpcr	14	1.44	1.14	7.86	2.59	1.21	-1.38	1
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_SB24	SB24	TM1	helix	gpcr	28	1.93	1.20	3.84	20.75	8.85	-11.90	1
5HT2C	5HT2C_SB24	SB24	TM1	helix	gpcr	28	1.88	0.56	5.77	20.75	8.77	-11.98	1
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_SB24	SB24	TM2	helix	gpcr	31	1.42	0.59	5.23	19.91	17.28	-2.63	0
5HT2C	5HT2C_SB24	SB24	TM2	helix	gpcr	31	0.98	0.76	2.40	19.91	20.65	0.74	0
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_SB24	SB24	TM3	helix	gpcr	36	2.12	1.52	5.25	16.10	10.78	-5.32	0
5HT2C	5HT2C_SB24	SB24	TM3	helix	gpcr	36	0.93	0.54	2.46	16.10	19.25	3.15	0
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_SB24	SB24	TM4	helix	gpcr	30	2.22	1.71	6.00	26.43	23.89	-2.54	0
5HT2C	5HT2C_SB24	SB24	TM4	helix	gpcr	30	0.58	0.45	0.86	26.43	27.00	0.57	0
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_SB24	SB24	TM5	helix	gpcr	39	2.77	2.41	2.89	5.64	7.54	1.91	1
5HT2C	5HT2C_SB24	SB24	TM5	helix	gpcr	39	1.28	0.43	2.61	5.64	4.10	-1.53	1
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_SB24	SB24	TM6	helix	gpcr	38	2.60	1.85	4.75	31.72	26.71	-5.01	0
5HT2C	5HT2C_SB24	SB24	TM6	helix	gpcr	38	1.52	0.76	4.21	31.72	30.39	-1.32	0
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_SB24	SB24	TM7	helix	gpcr	30	1.98	1.26	6.17	27.10	31.89	4.79	0
5HT2C	5HT2C_SB24	SB24	TM7	helix	gpcr	30	1.90	1.16	2.83	27.10	27.95	0.85	3
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_SB24	SB24	ECL1	loop	gpcr	4	2.19	2.18	N/A	N/A	N/A	N/A	0
5HT2C	5HT2C_SB24	SB24	ECL1	loop	gpcr	4	0.83	0.82	N/A	N/A	N/A	N/A	0
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_SB24	SB24	ECL2	loop	gpcr	10	27.50	19.04	N/A	N/A	N/A	N/A	1
5HT2C	5HT2C_SB24	SB24	ECL2	loop	gpcr	10	13.80	8.42	N/A	N/A	N/A	N/A	1
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_SB24	SB24	ICL1	loop	gpcr	4	2.32	2.30	N/A	N/A	N/A	N/A	0
5HT2C	5HT2C_SB24	SB24	ICL1	loop	gpcr	4	2.22	2.22	N/A	N/A	N/A	N/A	0
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_SB24	SB24	ICL2	loop	gpcr	20	19.28	10.60	N/A	N/A	N/A	N/A	7
5HT2C	5HT2C_SB24	SB24	ICL2	loop	gpcr	20	8.15	2.75	N/A	N/A	N/A	N/A	4
5HT2C_GNAQ+GNB1+GNG2	5HT2C_GNAQ+GNB1+GNG2_SB24	SB24	ICL3	loop	gpcr	2	23.71	15.82	N/A	N/A	N/A	N/A	0
5HT2C	5HT2C_SB24	SB24	ICL3	loop	gpcr	2	23.93	18.35	N/A	N/A	N/A	N/A	0

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BoltzMaker Report

Family coverage

Overall shift statistics

SSE motif shifts (apo vs holo)

Per-motif Ca RMSD

Motif x target RMSD