BoltzMaker SSE Comparison | Marc C. Deller

Family coverage

Family	Status	Detail
EGFR	OK	7 motif row(s) across 1 target(s), annotator=kinase

1 target(s), 7 motif(s) compared
Mean Ca RMSD: 0.27 A (median 0.23 A) — largest shift: 0.53 A at EGFR_FRAG1 / alphaC_Glu
Mean centroid shift: 0.19 A
Flagged phi/psi outlier residues: 8
Kinase state changes detected: 0 DFG, 0 alphaC

Identity						Shift			Backbone	Kinase state
Family	Target	Ligand	Motif	Kind	Source	N res	RMSD (A)	Centroid delta (A)	Flagged phi/psi	DFG apo	DFG holo	DFG delta	alphaC apo	alphaC holo	alphaC delta
EGFR	EGFR_FRAG1	FRAG1	DFG	loop	kinase	3	0.21	0.16	0	out	out	False	out	out	False
EGFR	EGFR_FRAG1	FRAG1	catalytic_loop	loop	kinase	3	0.26	0.24	0	out	out	False	out	out	False
EGFR	EGFR_FRAG1	FRAG1	hinge	loop	kinase	3	0.16	0.13	0	out	out	False	out	out	False
EGFR	EGFR_FRAG1	FRAG1	pocket_scaffold	loop	kinase	73	0.47	0.00	8	out	out	False	out	out	False
EGFR	EGFR_FRAG1	FRAG1	alphaC_Glu	point	kinase	1	0.53	0.53	0	out	out	False	out	out	False
EGFR	EGFR_FRAG1	FRAG1	catalytic_Lys	point	kinase	1	0.06	0.06	0	out	out	False	out	out	False
EGFR	EGFR_FRAG1	FRAG1	gatekeeper	point	kinase	1	0.23	0.23	0	out	out	False	out	out	False